http://stdj.scienceandtechnology.com.vn/index.php/stdj/issue/feed Science and Technology Development Journal 2021-09-21T23:17:32+00:00 Phuc Van Pham pvphuc@vnuhcm.edu.vn Open Journal Systems http://stdj.scienceandtechnology.com.vn/index.php/stdj/article/view/3781 Phenolic compounds from the lichen Parmotrema cristiferum (Taylor) Hale 2021-09-21T23:17:32+00:00 Nguyen Thi Ngoc Van ntnvan101096@gmail.com Nguyen Mong Anh Nguyet anhnguyetnguyet2299@gmail.com Tran Thai Bao baokiwia@gmail.com Nguyen Thi Le Thuy thuy.ntl@ou.edu.vn Bui Thanh Tung 1553010235tung@ou.edu.vn Pham Nguyen Kim Tuyen phngktuyen@gmail.com Nguyen Thi Hoai Thu nguyenthihoaithu@ump.edu.vn Nguyen Thi Anh Tuyet tuyetnta@hcmue.edu.vn Huynh Bui Linh Chi hainhanchi@yahoo.com.vn Nguyen Kim Phi Phung kimphiphung@yahoo.fr Ngo Thi Thuy Duong nttduong@hcmus.edu.vn <p><strong>Introduction</strong>: Lichens are fungal and algal or cyanobacterial symbioses resulting in the production of specific metabolites with a great variety of effects such as antimycobacterial, antiviral, antiinflammatory, antipyretic and antiproliferative. Parmotrema cristiferum (Taylor) Hale, a species of foliose lichen, was collected at Champasack Province, Laos in April 2015. This paper describes the isolation and structure elucidation of nine compounds isolated from this lichen.</p> <p><strong>Methods</strong>: Phytochemical investigations of the chloroform extract of the lichen P. cristiferum led to the isolation of nine pure compounds. Their chemical structures were elucidated by extensive HR-ESI-MS and 1D and 2D-NMR spectroscopic analysis, and comparison with previously published data.</p> <p><strong>Results</strong>: From the studied lichen, nine compounds, orcinol (<strong>1</strong>), orsellinic acid (<strong>2</strong>), atranol (<strong>3</strong>), methyl beta - orsellinate (<strong>4</strong>), atranorin (<strong>5</strong>), diffractaic acid (<strong>6</strong>), lecanoric acid (<strong>7</strong>), bailesidone (<strong>8</strong>), and tinctorinone (<strong>9</strong>) were isolated, structurally elucidated and evaluated for their a-glucosidase inhibitory activity.</p> <p><strong>Conclusions</strong>: Among isolated compounds, except 2, 4, and 7, the remaining six compounds were known for the first time from the lichen P. cristiferum. All these compounds were inactive in the a-glucosidase enzyme inhibitory assay.</p> 2021-09-21T00:00:00+00:00 ##submission.copyrightStatement##