http://stdj.scienceandtechnology.com.vn/index.php/stdj/issue/feed 2025-08-20T10:20:27+07:00 Phan Bach Thang pbthang@inomar.edu.vn Open Journal Systems http://stdj.scienceandtechnology.com.vn/index.php/stdj/article/view/4485 2025-08-20T10:19:29+07:00 Nhu Hoa Thi Tran ttnhoa@hcmus.edu.vn Nguyen Bao Tran baotran15803@gmail.com Nguyen Do Quynh Nhu nguyendoquynhnhu.1999vta@gmail.com Do Thao Anh dthaoanh144@gmail.com Le Hong Tho lehongtho562002@gmail.com Hanh Kieu Thi Ta ttkhanh@hcmus.edu.vn Quang Ngoc Tran tnquang@inomar.edu.vn

<h1><strong>Abstract</strong></h1> <p><strong>Introduction: </strong>Pesticide residues in food remain one of the unresolved concerns in recent years. Porous materials such as metal organic frameworks (MOFs), when combined with the localized surface plasmon resonance (LSPR) effect of silver nanoparticles (Ag NPs), enable label-free detection of analyte concentrations with high sensitivity. This approach is particularly effective in the detection of tebuconazole (TB) residues, a fungicide known for its persistence and potential health risks contributing to environmental protection and food safety.</p> <p><strong>Methods: </strong>Ag NPs were synthesized in a pre-prepared Zeolitic imidazolate framework&nbsp;(ZIF) solution, using a chemical reduction method, achieving relatively high uniformity. For surface-enhanced Raman scattering (SERS) applications, a self-assembled monolayer coating was fabricated on filter paper (FP) substrates by taking advantage of the strong absortion of Ag@Co-Zn-ZIF (Ag@CZZ) nanocomposites to cellulose fibers.</p> <p><strong>Results: </strong>UV–vis spectroscopy revealed that the LSPR wavelength of the Ag NPs is 419 nm, while XRD analysis confirmed the (111) plane of the face-centered cubic (FCC) crystalline structure of Ag. Morphologically, the synthesized nanoparticles exhibit a unique “popcorn-like” structure with an average size of approximately 408 nm, as demonstrated by field-emission scanning electron microscopy (FESEM). Energy-dispersive X-ray spectroscopy (EDS) shows the presence of elements constituting the popcorn-like Ag@CZZ. Moreover, characteristic vibrations from the ZIF structure were identified in the Raman spectra. The FP/Ag@CZZ SERS substrate for monitoring TB concentration was successfully established, with a limit of detection (LOD) calculated to be 3.08 × 10^-8 M.</p> <p><strong>Conclusion: </strong>Leveraging the LSPR effect of Ag NPs and the structural properties of ZIF, a simple and rapid fabrication method was used to develop a flexible and effective FP/Ag@CZZ SERS substrate. This platform exhibited high sensitivity in detecting and monitoring changes in TB concentration, opening promising opportunities for improving the detection limits of pesticide residues in agricultural and environmental monitoring.</p> <p><strong>Keywords: </strong>Co-Zn-ZIF, Ag@CZZ, Popcorn-like, Tebuconazole</p>

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