Science and Technology Development Journal <p><span id="result_box" class="" lang="en"><span title="Tạp chí Phát triển Khoa học và Công nghệ (PTKH&amp;CN) của Đại học Quốc gia thành phố Hồ Chí Minh (ĐHQG-HCM) được thành lập từ năm 1997, ra số đầu tiên vào tháng 1 năm 1998. Từ năm 2006 Tạp chí đã"><strong>Science and Technology Development Journal</strong> (STDJ), Vietnam National University - Ho Chi Minh City (VNU-HCM) was established in 1997. And the first issue was published in January 1998 with </span><span title="đăng ký mã số chuẩn quốc tế ISSN 1859-0128.">ISSN 1859-0128. </span><span title="Từ đó cho đến nay, Tạp chí PTKH&amp;CN đã trở thành diễn đàn khoa học quan trọng nhất của đội ngũ cán bộ nghiên cứu, giảng viên, nghiên cứu sinh của ĐHQG-HCM và cũng là diễn đàn khoa học công nghệ đáng tin cậy của">Since then, STDJ has become the most important scientific forum of scientists from VNU-HCM as well as</span><span title="nhiều nhà nghiên cứu, giảng viên các trường đại học khác tại Việt Nam."> other universities. </span><span title="Tạp chí đã trải qua 20 năm phát triển và đã trở thành nhịp cầu giao lưu khoa học, cũng như làm phong phú tài liệu tham khảo cho đội ngũ giảng viên, nghiên cứu sinh, sinh viên ĐHQG-HCM nói riêng và các Trường đại">The magazine has undergone 20 years of development and has become a bridge for scientific exchanges, as well as enriching reference materials for the faculty, doctoral students, students of VNU-HCM in particular and other universities, institutes... </span></span></p> <p><span id="result_box" class="" lang="en"><span title="học phía Nam nói chung. "><br></span><span title="Tính đến hết năm 2016 Tạp chí đã xuất bản được 276 số với 2714 bài nghiên cứu của các nhà khoa học, cán bộ trong và ngoài ĐHQG-HCM trong 5 lĩnh vực nghiên cứu: Kỹ thuật và Công nghệ, Khoa học Tự nhiên,">By the end of 2016, the journal has published 276 issues with 2714 research articles in five areas of research: Engineering and Technology, Natural Sciences, </span><span title="Khoa học Xã hội và Nhân văn, Kinh tế luật và Khoa học Quản lý, Khoa học Trái đất và Môi trường tương ứng với 5 chuyên san chuyên ngành của Tạp chí.">Social Sciences and Humanities, Economics of Law and Management Sciences, Earth Sciences and Environment corresponding to 5 specialized journals of the Journal. </span></span></p> <p><span id="result_box" class="" lang="en"><span title="Tạp chí đã được phát hành tại các thư viện của các đơn vị thành viên của ĐHQG-HCM, các Sở Khoa học Công nghệ của các tỉnh thành trên cả nước và được Hội đồng học hàm Giáo sư Nhà nước đánh giá cao.">The magazine has been widely indexed in the various libraries at Vietnam. </span></span></p> <p><span id="result_box" class="" lang="en"><span title="Từ tháng 12/2006 Tạp chí đã nhận được sự giúp đỡ của tổ chức mạng quốc tế về các xuất bản phẩm khoa học thuộc Hội đồng khoa học quốc tế để tham gia vào mạng lưới các Tạp chí Khoa học quốc tế. "><br></span><span title="Hiện nay tạp chí bao gồm 5 chuyên san sau đây: ">The journal currently consists of the following five sections:<br></span><span title="• Kỹ thuật và Công nghệ, ">• Engineering and Technology</span></span></p> <p><span id="result_box" class="" lang="en"><span title="• Khoa học Tự nhiên, ">• Natural Sciences</span></span></p> <p><span id="result_box" class="" lang="en"><span title="• Khoa học Xã hội và Nhân văn, ">• Social Sciences and Humanities</span></span></p> <p><span id="result_box" class="" lang="en"><span title="• Kinh tế luật và Khoa học Quản lý, ">• Economics, Law and Management</span></span></p> <p><span id="result_box" class="" lang="en"><span title="• Khoa học Trái đất và Môi trường">• Sciences of Earth and Environment</span></span></p> <p><span class="" lang="en"><span title="• Khoa học Trái đất và Môi trường"><span id="result_box" class="" lang="en">• Health Sciences : It includes work from basic science, clinical science, dental, nursing and other related medical fields. <br></span></span></span></p> Viet Nam National University Ho Chi Minh City en-US Science and Technology Development Journal 1859-0128 <p>Copyright The Author(s) 2018. This article is published with open access by Vietnam National University, Ho Chi Minh city, Vietnam. This article is distributed under the terms of the&nbsp;<a href="" target="_blank" rel="noopener">Creative Commons Attribution License (CC-BY 4.0)</a> which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.&nbsp;</p> Chemical constituents of the ethyl acetate extract from the leaf of mugwort (Artemisia vulgaris L.) <p><strong>Introduction</strong>: Mugwort (<em>Artemisia vulgaris</em> L.) is a familiar herbal medicine and also a daily vegetable. It is one of the ingredients in the famous remedy "Cao ích mẫu" specializing in menstrual disorders or the omelet with mugwort that helps save blood flow to the brain to treat headaches. In both traditional medicine and the new drugs, diseases are usually treated by mugwort as diabetes, epilepsy combination for psychoneurosis, depression, irritability, insomnia, anxiety, and stress. To demonstrate the medicinal uses, the chemical constituents of this herbal were continually studied.</p> <p><strong>Methods</strong>: The leaves of mugwort were collected in Ba Ria - Vung Tau province, Vietnam. The plant was identified by the late pharmacist and botanist Binh Duc Phan. A voucher specimen (AV001) was deposited in the herbarium of the Department of Organic Chemistry, VNUHCM–University of Science. Dried leaf powder of <em>A. vulgaris</em> (11 kg) was extracted with methanol and evaporated under reduced pressure to give a methanol extract (910 g), which was dissolved in methanol-water (1:9) and then successively partitioned with petroleum ether, chloroform, and ethyl acetate. From the previously researched ethyl acetate fraction, nine compounds were isolated: six known phenolic compounds (luteolin, 6-methoxyluteolin, eupatilin, o-coumaric acid, vanillic acid, and protocatechuic acid), sinapyl alcohol diisovalerate, vulgarin, and one new compound (artanoic acid).</p> <p><strong> Results</strong>: In this research, ethyl acetate fraction was also studied. From subfraction EA4, six compounds were isolated by three skeletons: phenolic compounds (5,4′ -dihydroxyflavone and 4-hydroxyphenyl acetate), phenyl propanoid (methyl 2-O-b -D-glucopyranosylcoumarate and 2-O-b -D-glucopyranosylcoumaric acid) and uracil (5-methyluracil and uridine). The structure of the isolated compounds was determined to base on 1D, 2D NMR spectra, HR-ESI-MS, and comparison with published data.</p> <p><strong>Conclusion</strong>: Particularly, four compounds (methyl 2-O-b -D-glucopyranosylcoumarate, 2-O-b -D-glucopyranosylcoumaric acid, 5-methyluracil, and uridine) were known for the first time from this species.</p> <p>&nbsp;</p> Truong Van Nguyen Thien Thien Tai Phan Tung Thanh Phan Lien Kim Thi Tran Nhu Tiet Thi Tran Phu Hoang Dang Linh Phi Nguyen Quang That Ton ##submission.copyrightStatement## 2019-12-31 2019-12-31 22 4 352 355 10.32508/stdj.v22i4.1744 title description none g Characterization of the silver thin films produced at different substrate temperatures <p><strong>Introduction</strong>: In recent decades, the antimicrobial surfaces/coating properties towards a longlasting microbicidal effect have drawn enormous attention by researchers, they have been developed and used in a wide variety of high-touch hospital devices as a potential approach.</p> <p><strong>Methods</strong>: In this work, Ag NPs was synthesized by sputtering method at the different annealing temperatures of 100◦C, 200◦C, 300◦C, and 400◦C.</p> <p><strong>Results</strong>: As a result, the as-synthesized Ag-300 exhibits the highest E. coli antibacterial performance compared with others. This can be attributed to the change of the Ag NPs toxicity based on the growth of nanoparticles during the deposition process related to the Ostwald ripening process, thermal activation and coalescence particles.</p> <p><strong>Conclusion</strong>: This work provides an essential insight into the antimicrobial activity of Ag NPs-based films synthesized through the vacuum deposition technique, resulting in opening a new approach for enhancing the antimicrobial efficacy and prospects.</p> <p>&nbsp;</p> <p>&nbsp;</p> Ton Nu Quynh Trang Le Thi Ngoc Tu Tran Van Man Vu Thi Hanh Thu ##submission.copyrightStatement## 2020-01-01 2020-01-01 22 4 356 364 10.32508/stdj.v22i4.1691 title description none g Four flavonols from the seed of Hibiscus sabdariffa. Linn. growing in Binh Thuan Province <p><strong>Introduction: </strong><em>Hibiscus sabdariffa</em> Linn. (Malvaceae) is a medicinal plant popularly distributed in Asian countries. As of 2019, no chemical investigations from the Vietnamese plant were found. This paper reported the isolation and elucidation of compounds isolated from the seeds of <em>Hibiscus sabdariffa</em> Linn. (Malvaceae) growing in Binh Thuan province.</p> <p><strong>Method: </strong>The maceration was applied to the seeds of the plant to afford the crude extract which was then fractionated by liquid-liquid extraction to obtain the ethyl acetate extract. The extract was carried out by using normal phase silica gel column chromatography and thin-layer chromatography. Analysis of spectroscopic data including HR-ESI-MS, 1D and 2D-NMR and a comparison of the NMR data with that in the literature led to the structural elucidation of isolated compounds.</p> <p><strong>Results: </strong>Four flavonols comprising quercetin 3-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside (<strong>1</strong>), quercetin 3-O-β-D-glucopyranoside (<strong>2</strong>), quercetin (<strong>3</strong>) and kaempferol (<strong>4</strong>) were isolated from the ethyl acetate extract.</p> <p><strong>Conclusions:</strong> This is the first time the isolated compounds were found from the seeds of this plant.</p> Pham Nguyen Kim Tuyen Truong Van Tien Tran The Anh Huy Nguyen Thi Hoa Huynh Bui Linh Chi Nguyen Thi Hoai Thu Huy Thuc Duong Nguyen Kim Phi Phung ##submission.copyrightStatement## 2019-11-30 2019-11-30 22 4 348 351 10.32508/stdj.v22i4.1690 title description none g