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Abstract

Two new limonoids, named nimbandiol A (1) and azadirachtolid E (2) were isolated from the leaves of Azadirachta indica, along with deoxyazadirachtolid (3), a known compound. Their structures were determined by spectroscopic methods and compared with literatures. Three compounds (1-3) showed moderate a-glucosidase inhibitory activities against Saccharomyces cerevisiae a-glucosidase with IC50 values of 38.7 mM, 85.76 mM and 48.24 mM, respectively.

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Article Details

Issue: Vol 14 No 2 (2011)
Page No.: 36-42
Published: Jun 30, 2011
Section: Natural Sciences - Research article
DOI: https://doi.org/10.32508/stdj.v14i2.1941

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Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Nguyen, N., Tran, Q., & Tran, Q. (2011). ALPHA-GLUCOSIDASE INHIBITORY LIMONOIDS FROM THE LEAVES OF AZADIRACHTA INDICA A. JUSS GROWN IN NINH THUAN PROVINCE. Science and Technology Development Journal, 14(2), 36-42. https://doi.org/https://doi.org/10.32508/stdj.v14i2.1941


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