Science and Technology Development Journal

Latest Articles

1. Special Issue

   Identification of COL11A1 single-gene polymorphisms in patients with primary angle-closure glaucoma

   Vo B., T., Hoang V., Bui L., Hoang V., Nguyen N., Nguyen T.

   According to a survey of the Rapid Assessment of Avoidable Blindness (RAAB) in Vietnam in 2015, glaucoma is the third most common cause of blindness after cataracts and fundus diseases, with a rate of 4%. Worldwide, studies on primary angle-closure glaucoma (PACG) have revealed approximately 50 genes and many related gene variants. In primary angle-closure glaucoma, COL11A1 was identified as one of the eight genes with the most important role related to the disease. There have been many studies analyzing gene mutations associated with eye diseases in Vietnam, but few studies have been conducted on PACG. Therefore, we focused on detecting some gene variants of COL11A1 in patients with PACG in several military hospitals.

   Published: 2024-03-31In press
2. Section: ENGINEERING AND TECHNOLOGY

   Investigating the effect of synthesis parameters on the structure and upconversion luminescent properties of NaYF4:Tm,Yb for anticounterfeiting printing ink

   Tuyen V., Tong N., Le H., Dung C., Van T.

   In this study, NaYF4:Tm,Yb upconversion microparticles were prepared by a hydrothermal method.

   Published: 2024-03-313275-3285
3. Section: ENGINEERING AND TECHNOLOGY

   Synthesis of Co3O4 electrodes by electrochemical deposition for water splitting reaction

   La H., Tran P., Khac T., Le G., Nguyen H., Pham V.

   The use of Ni foam substrates for the growth of catalysts is a common practice in electrochemical water splitting reactions, although their stability in some electrolytes can be problematic, hindering the scalability of synthesis. This study aims to explore alternative substrates for catalyst growth, focusing on cobalt oxide (Co3O4) due to its potential in enhancing electrochemical water splitting efficiency.

   Published: 2024-03-313294-3300
4. Section: ENGINEERING AND TECHNOLOGY

   Controlling the absorption region of multi-shaped silver nanoparticles for SERS applications

   Nguyen L., N., T., Luong H., N., Pham N., B., T., Duy L., T., Tran C., K., Nguyen N., P., Dang V. Q.

   Silver nanoparticles (Ag NPs) are pivotal in advancing surface-enhanced Raman scattering (SERS) due to their exceptional plasmonic properties. Yet, conventional synthesis methods often fail to precisely control their shape and size, impacting SERS efficiency. This study introduces a novel synthesis approach using hydrogen peroxide (H2O2) to tailor Ag NP morphologies, aiming to optimize their plasmonic resonance for improved SERS detection of hazardous substances.

   Published: 2024-03-313308-3314
5. Section: ENGINEERING AND TECHNOLOGY

   Biosynthesis of Staphylococcus aureus OS-silver nanoparticles and their antimicrobial and protective effects on coated paper money

   Olusola-Makinde O., Ajayi O., Ogidi C.

   Currency notes harbor and transmit infectious microorganisms if handled without proper care. Hence, in this study, silver nanoparticles biosynthesized from autochthonous S. aureus OS (S-AgNPs) isolated from Nigeria currency notes (Naira) were used to assess the antimicrobial activity of S-AgNPs against the pathogenic money microbiome and to determine their protective effect on coated currency notes.

   Published: 2024-03-313347-3356
6. Section: NATURAL SCIENCES

   Impacts of basis sets, solvent models, and NMR methods on the accuracy of 1H and 13C chemical shift calculations for biaryls: a DFT study

   Nguyen T.

   Biaryls are core structures composed of chiral ligands, organocatalysts, biologically active natural products and biopolymer lignins. In this study, the effects of basis sets, solvent models, and NMR methods on the accuracy of ¹H/¹³C NMR chemical shift calculations for biaryl structures were evaluated.

   Published: 2024-03-313339-3346
7. Section: NATURAL SCIENCES

   Polycyclic aromatic hydrocarbons (PAHs) in sediment environments in Vietnam: Analytical methods and contamination status

   Nguyen D., H., Hoang Q., A., Tu B., M., Tran M., T., Dang M., H., G., Hoang B., N., Vu V., T., Nguyen T., H., Y., Shin T.

   Polycyclic aromatic hydrocarbons (PAHs) are prevalent organic pollutants that garner attention due to their toxicity and carcinogenic properties. These hydrophobic compounds tend to accumulate in the organic components of sediments, posing significant ecological risks.

   Published: 2024-03-313269-3274
8. Section: NATURAL SCIENCES

   A simple method to estimate the pKa values of four fluorescent proteins based on measuring their pH-dependent absorbance spectra

   BUI T., Y., H., Tran T. N.

   The Nobel Prize in Chemistry 2014 greatly recognized the application of fluorescent proteins (FPs) in superresolution imaging techniques. Subsequently, there has been a significant surge in FP-related investigations. Reversibly photoswitchable fluorescent proteins (rsFPs) are currently attracting much interest from scientists worldwide because of their unique ability to switch between bright and dark states. The pH-dependent photophysical behavior of rsFPs is mostly controlled by the equilibrium between four distinct states of the chromophores in FPs: trans-protonated, trans-deprotonated, cis-protonated, and trans-deprotonated. Thus, the pKa values of rsFP in general and its chromophore, in particular, are crucial factors in determining the fluorescence output of the settings containing rsFPs in different environments.

   Published: 2024-03-313286-3293
9. Section: NATURAL SCIENCES

   Biofilm biosynthesis of Priestia megaterium M1VB5 strain Muc Son Thanh Hoa paper mill

   Dang N., Phan T., Tran H., Le T., Nguyen L., Nguyen T., Ngo H., Cao S.

   Strain M1VB5, isolated from slime in paper machine pipes, is studied for its role in slime formation. This slime, comprised of microorganisms, binds and adheres to pipes, potentially leading to clogs, process inefficiencies, and machinery contamination.

   Published: 2024-03-313301-3307
10. Section: NATURAL SCIENCES

    Investigate the influence of a CagA-negative Helicobacter pylori strain, GD13, on nonhomologous end joining-mediated repair of proximal DNA double-strand breaks in GCV6 cells

    Vo-Ho M.,-P., Nguyen T.,-V., Pham D. T.-H.

    Mammalian cells infected with Helicobacter pylori show an accumulation of DNA double-strand breaks (DSBs). Previous studies have shown that the virulence factor CagA of H. pylori induces genomic instability in host cells. Most DSBs in infected cells are repaired by nonhomologous end-joining (NHEJ) pathways. Indeed, impairment of NHEJ-mediated DSB repair may lead to genetic alterations and contribute to the development of gastric cancer. Nonetheless, the impacts of H. pylori and its virulence factor, CagA, on the efficacy of NHEJ are poorly defined. This study aimed to reveal the effect of GD13, a CagA-H. pylori strain isolated in Vietnam, on the NHEJ-mediated repair of DSBs in host cells. For this purpose, we utilized GCV6 cells with an NHEJ-reporter substrate, which has been proven to be an appropriate model for evaluating the repair efficiency of NHEJ in H. pylori-infected cells. The level of interleukin-8 released into the cell culture supernatant was measured by ELISA. Our findings suggest that the reference CagA+ 26695 strain impaired the NHEJ-mediated repair of double-strand breaks (DSBs), whereas the GD13 strain has not exhibited any discernible effect thus far. In addition, H. pylori strain GD13 triggered a lower level of interleukin-8 secretion in GCV6 cells than did the CagA-positive strain 26695.

    Published: 2024-03-313333-3338