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VNUHCM Journal of

Science and Technology Development

An official journal of Viet Nam National University Ho Chi Minh City, Viet Nam since 1997

ISSN: 1859-0128
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SYNTHESIS OF NOVEL URSOLIC ACID DERIVATIVES

Phuong Thanh Tran 1, *
Phung Kim Phi Nguyen 2
Quan Thanh Pham 1
Danh Thanh Tong 1

  1. University of Technology, VNU-HCM
  2. University of Science, VNU-HCM
Correspondence to: Phuong Thanh Tran, University of Technology, VNU-HCM. Email: pvphuc@hcmuns.edu.vn.
Volume & Issue: Vol. 14 No. 3 (2011) | Page No.: 49-53 | DOI: 10.32508/stdj.v14i3.1963
Published: 2011-09-30

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Copyright © 2011 by the author(s).

Copyright The Author(s) 2023. This article is published with open access by Vietnam National University, Ho Chi Minh city, Vietnam. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

Some novel Ursolic Acid (UA) derivatives were designed and synthesized with substitution at positions of C-3-OH and C-28-COOH of UA, the product (1)-(6) has the yeild higher than (7)-(9), in reaction UA with CDI (10) has medium yield. These compounds showed ability ester reaction to product was easily, form these products give pharmacological activity better than UA .Their structures were confirmed using 1H-NMR.

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