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Abstract

One of reactions to create the link of carbon-carbon bond is cross-coupling reaction between alkyl tosylate and Grignard reagent in the presence of controlled copper catalysis at -78 °C. Under the activation of ultrasound irradiation, this coupling is taken place quickly in about 30-45 minutes to give product in good yield.



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Issue: Vol 10 No 3 (2007)
Page No.: 42-46
Published: Mar 31, 2007
Section: Article
DOI: https://doi.org/10.32508/stdj.v10i3.2762

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Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Ngoc Nhuan, D., Thach, L., Hieu, D., & Hao, N. (2007). APPLICATION OF ULTRASOUND IN CROSS COUPLING REACTIONS OF ALKYL TOSYLATES AND GRIGNARD REAGENTS. Science and Technology Development Journal, 10(3), 42-46. https://doi.org/https://doi.org/10.32508/stdj.v10i3.2762

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