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Abstract
Cefuroxime, a second generation cephalosporin antibiotic, is synthesized from starting materials 7-ACA (7-amino cephalosporinic acid) and SMIA (2-furanyl- (Z)-2-methoxyiminoacetic acid ammonium salt). The study showed that the product could be prepared via a 4 step scheme to obtain cefuroxime in good total yield of 42 %.
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Article Details
Issue: Vol 18 No 4 (2015)
Page No.: 111-116
Published: Dec 30, 2015
Section: Natural Sciences - Research article
DOI: https://doi.org/10.32508/stdj.v18i4.914
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Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
How to Cite
Nguyen, T., Doan, N., & Dang, T. (2015). Preparation of cefuroxime from 7-ACA. VNUHCM Journal of Science and Technology Development, 18(4), 111-116. https://doi.org/https://doi.org/10.32508/stdj.v18i4.914
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