Screening for some biological activities of cultured cordyceps neovolkiana

Abstract

Cordyceps has been demonstrated to possess a myriad of biological compounds and effects. There are various strains of Cordyceps. In this study, we evaluated some biological activities of cultured Cordyceps neovolkiana extracts. The result exhibited that all C. neovolkiana extracts almost showed no toxicity effect on HepG2 cells at the concentration of 100 μg/ml. Besides, all C. neovolkiana extracts also were not α-glucosidase inhibitory activity at the concentration from 1000 to 8000 μg/ml. However, some extracts had ABTS• free radical scavenging potential with IC50 values between 4129.92 ± 25.12 and 4926.25 ± 41.01 μg/ml. In addition, at 200 μg/ml, the EtOH extract exhibited 64.57 ± 6.30 % (p<0.001) of PBMC proliferation inhibition. In conclusion, these data revealed biological activities of cultured C. neovolkiana, suggesting that further studies would be necessary.