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Abstract

Cordyceps has been demonstrated to possess a myriad of biological compounds and effects. There are various strains of Cordyceps. In this study, we evaluated some biological activities of cultured Cordyceps neovolkiana extracts. The result exhibited that all C. neovolkiana extracts almost showed no toxicity effect on HepG2 cells at the concentration of 100 μg/ml. Besides, all C. neovolkiana extracts also were not α-glucosidase inhibitory activity at the concentration from 1000 to 8000 μg/ml. However, some extracts had ABTS• free radical scavenging potential with IC50 values between 4129.92 ± 25.12 and 4926.25 ± 41.01 μg/ml. In addition, at 200 μg/ml, the EtOH extract exhibited 64.57 ± 6.30 % (p<0.001) of PBMC proliferation inhibition. In conclusion, these data revealed biological activities of cultured C. neovolkiana, suggesting that further studies would be necessary.



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Article Details

Issue: Vol 20 No K3 (2017)
Page No.: 106-112
Published: Jun 30, 2017
Section: Engineering and Technology - Research article
DOI: https://doi.org/10.32508/stdj.v20iK3.1099

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Creative Commons License

Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Nguyen, C.-D., Huynh, T., & Dinh, M.-H. (2017). Screening for some biological activities of cultured cordyceps neovolkiana. Science and Technology Development Journal, 20(K3), 106-112. https://doi.org/https://doi.org/10.32508/stdj.v20iK3.1099

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