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Friedel-crafts acylation of aromatic compounds using Triflat bismuth

Phuong Hoang Tran 1, *
Thanh Duy Anh Nguyen 1
Thach Ngoc Le 1
  1. University of Science, VNU-HCMC
Correspondence to: Phuong Hoang Tran, University of Science, VNU-HCMC. Email: pvphuc@vnuhcm.edu.vn.
Volume & Issue: Vol. 17 No. 2 (2014) | Page No.: 10-14 | DOI: 10.32508/stdj.v17i2.1310
Published: 2014-06-30

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Copyright The Author(s) 2023. This article is published with open access by Vietnam National University, Ho Chi Minh city, Vietnam. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

Friedel-Crafts acylation of aromatic compounds with acetic anhydride as acylating reagent was investigated in the presence of Lewis acid. Bismuth trifluoromethanesulfonate was found to be efficient catalyst for Friedel-Crafts acetylation under mild conditions. Bismuth triflate is safe-to-handle, simple and clean work-up, good yield and short reaction time

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