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Introduction: Euphorbia tirucalli L. is a medicinal plant popularly distributed in Asian countries. In Vietnam, only one study on the polar extract the plant Euphorbia tirucalli growing in Binh Thuan province, Vietnam was reported, revealing several phenolic components. As of 2019, no chemical reports on the non-polar extract from the Vietnamese plant were found. This research described the isolation and elucidation of compounds isolated from the non-polar extract of E. tirucalli growing in Binh Thuan province.

Method: The n-hexane extract of this plant was carried out by using normal phase silica gel column chromatography, thin-layer chromatography, and gel chromatography (Sephadex LH-20). Analysis of spectroscopic data and a comparison of the NMR data with that in the literature led to the structural elucidation of isolated compounds.

Results: Three terpenoid compounds, euphol (1), lupenone (2), and vomifoliol (3), along with ergosterol peroxide (4), ferulic acid (5), and vanillic acid (6) were isolated and elucidated.

Conclusions: Among them, compound 3 and 4 were reported in the first time from E. tirucalli.


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Issue: Vol 22 No 2 (2019)
Page No.: 247-252
Published: Jun 19, 2019
Section: Natural Sciences - Research article

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Copyright: The Authors. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

 How to Cite
Duong, H. (2019). A further investigation on the chemical constituents from Euphorbia tirucalli growing in Binh Thuan province. VNUHCM Journal of Science and Technology Development, 22(2), 247-252.

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