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BIOACTIVITIES AND CHEMICAL CONSTITUENTS OF A VIETNAMESE MEDICINAL PLANT VANG SE JASMINUM SUBTRIPLINERVE BLUME

Huong Thi Diem Nguyen 1, *
Son Hong Phan 1
Huong Dang Thien Bui 2
Hoai Thi Cam Ho 1
Mai Thi Thanh Nguyen 1
  1. University of Sciences, VNU - HCM
  2. Insititute of Hygiene and Public Health of HCM city
Correspondence to: Huong Thi Diem Nguyen, University of Sciences, VNU - HCM. Email: pvphuc@hcmuns.edu.vn.
Volume & Issue: Vol. 15 No. 3 (2012) | Page No.: 37-44 | DOI: 10.32508/stdj.v15i3.1815
Published: 2012-09-30

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Copyright The Author(s) 2023. This article is published with open access by Vietnam National University, Ho Chi Minh city, Vietnam. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

From the total crude ethanol extract of Jasminum subtriplinerve Blume.’s leaves and stems, (Vang se in Vietnamese), four extracts were obtained by partitioning with petroleum ether, cloroform, ethyl acetate and n-butanol solvents. These four extracts were tested for antioxydative activity, determined using the DPPH●.radical scavenging and nitric oxyde-inhibitory assay. All the extracts showed antioxidative activity except the petroleum ether extracts. Among the crude extracts, the acetate ethyl extract was the most potent extract in both assays with the SC50 values of 8.2 μg/mL and 80.7 μg/mL, respectively. From the VS3 substract, three compounds were isolated, including two acids namely 3,4- dihidroxybenzoic acid (1), 3,4,5-trihidroxybenzoic acid (2) and a glycoside, verbascoside (3). The structure of those compounds was elucidated by spectrometric methods IR, MS, LC-MS, 1D-NMR, and 2D-NMR.

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