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VNUHCM Journal of

Science and Technology Development

An official journal of Viet Nam National University Ho Chi Minh City, Viet Nam since 1997

ISSN: 1859-0128
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STUDY ON PREPARATION OF CHITOSAN NANOPARTICLE AS PROTEIN DELIVERY CARRIER FOR DRUG DELIVERY APPLICATION

Tuyet Thi Anh Duong 1, *
Khuong Quoc Vo 1
Phuong Hue Phan 1
Phong Thi Phuong Nguyen 1

  1. University of Science, VNU-HCM
Correspondence to: Tuyet Thi Anh Duong, University of Science, VNU-HCM. Email: pvphuc@hcmuns.edu.vn.
Volume & Issue: Vol. 14 No. 4 (2011) | Page No.: 54-61 | DOI: 10.32508/stdj.v14i4.2048
Published: 2011-12-30

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Copyright © 2011 by the author(s).

Copyright The Author(s) 2023. This article is published with open access by Vietnam National University, Ho Chi Minh city, Vietnam. This article is distributed under the terms of the Creative Commons Attribution License (CC-BY 4.0) which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. 

Abstract

This work investigates the polyanion initiated gelation process in fabricating chitosan (CS)-tripolyphosphate (TPP) nanoparticle intended to be used as protein delivery carrier. Variations in cross-linking agents, CS/TPP weight ratio and solution pH were investigated. The chitosan nanoparticles were characterized by several analytical techniques such as FT-IR, XRD, FE_SEM and TEM. Finally, protein loading efficiency (LE) and protein loading capacity (LC) were investigated.

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